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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NUAK1
All Species:
21.52
Human Site:
S394
Identified Species:
36.41
UniProt:
O60285
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60285
NP_055655.1
661
74305
S394
E
S
P
S
K
L
S
S
K
R
P
K
G
I
L
Chimpanzee
Pan troglodytes
XP_001161041
661
74289
S394
E
S
P
S
K
L
S
S
K
R
P
K
G
I
L
Rhesus Macaque
Macaca mulatta
XP_001098986
667
74748
S400
E
S
P
S
K
L
S
S
K
R
P
K
G
I
L
Dog
Lupus familis
XP_538417
666
74288
S399
E
S
P
N
K
L
T
S
K
R
P
K
G
I
L
Cat
Felis silvestris
Mouse
Mus musculus
Q641K5
658
73643
S395
E
S
P
S
K
L
S
S
K
R
P
K
G
I
L
Rat
Rattus norvegicus
Q66HE5
630
69934
E373
G
S
T
G
P
G
L
E
R
Q
H
S
L
K
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508265
661
73136
R394
P
S
K
S
G
S
K
R
P
K
S
I
L
K
K
Chicken
Gallus gallus
Q9IA88
798
88848
S386
L
T
S
E
T
L
R
S
S
L
L
Y
Q
Q
P
Frog
Xenopus laevis
NP_001088596
570
64876
D313
R
S
S
R
P
L
W
D
N
N
S
K
M
R
C
Zebra Danio
Brachydanio rerio
Q6NSM8
1187
130949
N716
N
H
L
F
R
P
A
N
Q
S
S
P
P
P
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_649991
1427
153426
S1017
T
N
A
N
T
S
A
S
A
T
C
A
L
P
V
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9TW45
1192
126331
A560
A
G
S
A
L
A
S
A
A
N
A
Q
K
H
Q
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P92958
512
58671
I254
D
L
I
P
R
M
L
I
V
D
P
V
K
R
I
Baker's Yeast
Sacchar. cerevisiae
P06782
633
72027
T373
S
L
E
S
S
E
D
T
P
A
F
N
E
I
R
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
97.9
91.7
N.A.
90.9
55.6
N.A.
84.2
26.1
48.5
23.5
N.A.
24.3
N.A.
22.4
N.A.
Protein Similarity:
100
99.8
98
94.4
N.A.
93.8
68
N.A.
88
42.8
61.4
36.2
N.A.
33.6
N.A.
35.8
N.A.
P-Site Identity:
100
100
100
86.6
N.A.
100
6.6
N.A.
13.3
13.3
20
0
N.A.
6.6
N.A.
6.6
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
20
N.A.
20
20
20
26.6
N.A.
33.3
N.A.
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
31.1
26.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
49.3
46.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
8
8
0
8
15
8
15
8
8
8
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
8
% C
% Asp:
8
0
0
0
0
0
8
8
0
8
0
0
0
0
0
% D
% Glu:
36
0
8
8
0
8
0
8
0
0
0
0
8
0
0
% E
% Phe:
0
0
0
8
0
0
0
0
0
0
8
0
0
0
0
% F
% Gly:
8
8
0
8
8
8
0
0
0
0
0
0
36
0
0
% G
% His:
0
8
0
0
0
0
0
0
0
0
8
0
0
8
0
% H
% Ile:
0
0
8
0
0
0
0
8
0
0
0
8
0
43
8
% I
% Lys:
0
0
8
0
36
0
8
0
36
8
0
43
15
15
15
% K
% Leu:
8
15
8
0
8
50
15
0
0
8
8
0
22
0
36
% L
% Met:
0
0
0
0
0
8
0
0
0
0
0
0
8
0
0
% M
% Asn:
8
8
0
15
0
0
0
8
8
15
0
8
0
0
0
% N
% Pro:
8
0
36
8
15
8
0
0
15
0
43
8
8
15
15
% P
% Gln:
0
0
0
0
0
0
0
0
8
8
0
8
8
8
8
% Q
% Arg:
8
0
0
8
15
0
8
8
8
36
0
0
0
15
8
% R
% Ser:
8
58
22
43
8
15
36
50
8
8
22
8
0
0
0
% S
% Thr:
8
8
8
0
15
0
8
8
0
8
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
8
0
0
8
0
0
8
% V
% Trp:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _